basic principles of blood transfusion ppt

If the blood cells clump together in response to the anti-Rh serum, it indicates that the blood is Rh-positive. Factors influencing agglutinationThe following factors affect the process of agglutination. In this report, "transfusion" refers to any situation in which a patient receives any component of human blood from a single or multiple donors. Approximately 22-35% of A2B individuals produce Anti-A1. Principles of . HOMOLOGUS:- It is the transfusion from another person. 1914Modern Anticoagulation is Born Citrate first used for blood anticoagulation purposes. Bed sores / decubitis ulcer / pressure sores, Blood Transfusion (a nursing procedure) by www.nursesinfosite.blogspot.com, Blood transfusion by M.Sc.Second year, 2020-21 Btach, SVBCON, Silvassa. Basic principles of blood transfusion must be based on the unique characteristics as well as the vascular structure of each blood group. PowerPoint Blood Donor Selection McGraw Hill Professional Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past-President of the American Board of Pathology 2. Volunteer blood donors must pass certain criteria, including the following: Must be at least 16 years of age, or in accordance with state law, Must pass the physical and health history exam given before donation. Normal plasma contains no anti-Rh anti-D antibodies. CuSO4 Hemoglobin determination Note: Other methods can also be used for this purpose. The SlideShare family just got bigger. Rosenfield and coworkers in 1960 proposed this system which assigns a number to each antigen as follows:D is Rh1C is Rh2E is Rh3c is Rh4e is Rh5The absence of an antigen is designated by a prefix negative sign, e. Anti-Rh agglutinins develop slowly 2-4 months. 2.1: Blood group antigens. Key Features: Delivers an applied, evidence-based foundation on the basic science underlying . . .., . 2. Removes end-products of metabolism: CO2, urea, creatinine 3. Albumin or EnzymesThe types of the medium used affect the agglutination. In 1665, an English physiologist, Richard Lower, successfully performed the first animal-to-animal blood transfusion that kept ex-sanguinated dogs alive by transfusion of blood from other dogs. DEFINITION It is the administration of packed red blood products separated in the blood bank from collected whole blood. Label a test tube. Click here to review the details. 1.6 Introductory Module: Guidelines and Principles for Safe Blood Transfusion Practice 11 1.7 Module Objectives 12 1.8 Planning Your Study 14 . But, the importance of ABO supersedes all From Petz and Swishers Clinical Practice of Transfusion Medicine, 2nd ed., 1989. medical staff 2011. regulations. The donor screening process also protects the safety of the transfusion recipient by . It is not used if the patient is hypovolemic. Post transfusion purpura Thrombocytopenia 5 to 21 days Patient makes an alloantibody in response to platelet antigens in the transfused blood that for a period of time (7-48days) causes destruction of autologous antigen-negative platelets. Murphy, Jr. develop the plastic collection bag. Free shipping for many products! Principle From patient From donor Cross-matching 1 Identify cause of deficien cy ABO, Rh ABO, Rh GXM 2 Replace only deficiency compone nt Antibody screening GSH 3 Blood produ ct should be as safe as posible Antibody identification Blood compone nts & plasma derivatives When electronic issue is not appropriate and in procedures with a high probability of requiring transfusion a maximum surgical blood ordering schedule (MSBOS) should be agreed between the surgical team and transfusion laboratory. 1, p. 2 (1961), The Discovery of Many OtherRed Cell Antigens Followed Rh (C, c, D, E, e, ) Kell (K, k, ) Kidd (Jka, Jkb, ) Duffy (Fya, Fyb, ) MNSs, Lewis (Lea, Leb) . The accompanying PowerPoint presentations are a resource for both lecturers teaching clinical skills and individual students who are either encountering a skill for the first time or want to update their knowledge. Each unit of blood is broken down into components, such as red blood cells, plasma, cryoprecipitated AHF,and platelets. Thank you for subscribing. Blood type A has the A antigen, blood type B has the B antigen, blood type AB has both A and B antigens, and blood type O has neither A nor B antigens. FRESH FROZEN PLASMA Used in case of multiple coagulation, deficiencies such as liver failure, warfarin OD, DIC, massive transfusion in bleeding patients, TTP, antithrombin III deficiency, hereditary angioma. initiating blood therapy. TYPES OF BLOOD TRANSFUSION AUTOLOGUS:- A donation of clients own blood before scheduled procedure. Islam M. Korayem, MD, PhD 2020/ HEMOSTASIS AND BLOOD TRANSFUSION Intended learning objectives: By the end of this note, you should be able to: - Define hemostasis and get familiar with different methods to achieve hemostasis in the operative field - Identify the mechanism of action of different hemostatic procedures - Outline the indications of blood transfusion and the different types of . Blood Transfusion - . (2) Via Apheresis: Machines with internal centrifuges separate a donors blood into individual components (e.g., platelets, plasma, RBCs, etc.). Laboratory resolution of parentage problems. This Anti-H of Oh is clinically significant, warm antibody reactive at 37C. AntigenAntigen is a substance which elicits immune response. objectives. Quality in blood and tissue establishments and hospital blood banks, 3: Care and selection of whole blood and component donors (including donors of pre-deposit autologous blood), 4: Premises and quality assurance at blood donor sessions, 5: Collection of a blood or component donation, 6: Evaluation and manufacture of bloodcomponents, 8: Evaluation of novel blood components, production processes and blood packs: generic protocols, 9: Microbiology tests for donors and donations: general specifications for laboratory test procedures, 10: Investigation of suspected transfusion-transmitted infection, 12: Donation testing (red cell immunohaematology), 13: Patient testing (red cell immunohaematology), 14: Guidelines for the use of DNA/PCR techniques in Blood Establishments, 15: Molecular typing for red cell antigens, 21: Tissue banking: tissue retrieval and processing, 23: Specification for the uniform labelling of blood, blood components and blood donor samples, 24: Specification for the uniform labelling of human tissue products using ISBT 128, 25: Standards for electronic data interchange within the UK Blood Transfusion Services, 26: Specification for blood pack base labels, 27: Specification for labelling consumables used in therapeutic product production, Annex 2: ISBT 128 check character calculation, Annex 5: Blood Components for Contingency Use, Annex 6: Advanced Therapy Medicinal Products (ATMPs), Bone Marrow and Peripheral Blood Stem Cell, 4: Safe transfusion right blood, right patient, right time and right place, 6: Alternatives and adjuncts to blood transfusion, 7: Effective transfusion in surgery and critical care, 8: Effective transfusion in medical patients, 9: EFFECTIVE transfusion in obstetric practice, 10: Effective transfusion inpaediatric practice, 12: Management of patients who do not accept transfusion, Guidance for HealthCare Practitioners involved in this role, Clinical Decision-Making and Authorising Blood Component Transfusion, Testing for red cell antigens and antibodies in the laboratory, Other clinically important blood groupsystems, Compatibility procedures in the hospital transfusion laboratory, Safe transfusion right blood, right patient, right time and right place, Alternatives and adjuncts to blood transfusion, Effective transfusion in surgery and critical care, Effective transfusion in medical patients, EFFECTIVE transfusion in obstetric practice, Effective transfusion inpaediatric practice, Management of patients who do not accept transfusion, 2.3: Testing for red cell antigens and antibodies in the laboratory, 2.6: Other clinically important blood groupsystems, 2.7: Compatibility procedures in the hospital transfusion laboratory. 1939/40Rh and Cause of HDFN Discovered Levine, Wiener, and colleagues combined their efforts in making these seminal discoveries From Netter Monograph Series. Objectives, An Introduction to the Principles of Transfusion Medicine Christopher J. Gresens, M.D. mohammed a. omair, mbbs, sf rheum organizer 341 med consultant, Progress and Future of Transfusion Medicine - . Landsteiners Rule If an antigen (Ag) is present on a patients red blood cells . Criterion Three Managing blood and blood product safety Blood must be stored and handled appropriately to prevent risk to patients Wastage of blood should be avoided Systems around receipt, storage, collection, and transport must address these risks Issue - outsourced blood provision services Storage and handling 7.7 Blood and blood products . Free shipping for many products! To prevent sensitisation and the risk of HDFN, RhD negative or Kell (K) negative girls and women of child-bearing potential should not be transfused with RhD or K positive red cells except in an emergency. what is naturopathic medicine?. A person can donate blood every 90 days (3 months). Free access to premium services like Tuneln, Mubi and more. what is blood made up of?. Activate your 30 day free trialto unlock unlimited reading. almost all hemolytic transfusion reactions are caused by, An introduction to 341 Medicine COURSE - . HOTLINE Reconstituted in 3 minutes; good for 4 hours. Place them in a sealed bag, return to the blood bank & transfusion investigation form must be filled. DURING THE PROCEDURE:- Note for the reactions. I 2 . blood may be need to be washed to remove the debris before re-infusion. RED BLOOD CELLS, WHITE BLOOD CELLS, PLASMA, CLOTTING 1940s Making Plasma Products Charles Drew starts the Blood for Britain program leading to the manufacture of large quantities of dried plasma. transfusion, Transfusion Medicine - . 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Patients should be under regular visual observation and, for every unit transfused, minimum monitoring should include: Pre-transfusion pulse (P), blood pressure (BP), temperature (T) and respiratory rate (RR). 1. 1900ABH Blood Group System IDd Karl Landsteiner discovers ABH system when he types individuals as (what we now call) group A, group B, and group O. group discussion Resources flip chart PowerPoint presentation Visit to blood bank with a brief introduction to basic lab working practices Questioning and continual evaluation of . From Transfusion, Vol. The number of blood units donated is about 13.6 million a year. Good luck! As a leading manufacturer and distributor, we as a company are fully dedicated to providing a wide range of advanced rapid in-vitro immune-diagnostic test systems and electrical bio-sensing systems, particularly blood glucose monitoring systems for home and professional use. If processed at once, 1-4 each unit (450 mL) of whole blood can be seperated into 1 unit of pRBCs and 1 unit of FFP. Clipping is a handy way to collect important slides you want to go back to later. 16671st DocumentedAnimal-to-Human Transfusion Jean Baptiste Denis infuses 15-year-old boy with lambs blood. In children 15mg/dl PRBC will increase hematocrit by 6% &Haemoglobin by 2g/dl. FFP administered through standard blood administration set. Prescribing decisions should be based on national guidelines as well as hospital-developed guidelines approved by the medical staff (Transfusion Committee). Use of blood products also puts patients with haemophilia at risk of additional complications, such as allergic and transfusion reactions, and fluid overload. We've updated our privacy policy. By whitelisting SlideShare on your ad-blocker, you are supporting our community of content creators. shanghai blood center qian kaicheng. Before a transfusion can take place, the donor's blood is tested against the recipient's serum, or plasma without the clotting proteins, to see if there is a reaction. EYPNqs Tap here to review the details. MANEUVER TO REPLACE BLOOD CELLS OR BLOOD PRODUCTS Looks like youve clipped this slide to already. Introduction Transfusion of blood and its products is very common medical procedure in the practice of modern medicine. It has millions of presentations already uploaded and available with 1,000s more being uploaded by its users every day. STAGES OF BLOOD TRANSFUSION Before transfusion:- Ask patient to state his full name & check the record. Instant access to millions of ebooks, audiobooks, magazines, podcasts and more.