how to reverse post finasteride syndrome how to reverse post finasteride syndrome

Its on an auto refill and I get 90 day supplies sent to me in the mail. I suspect that 2 mg would be adequate, but if my doc prescribes two 1mg pills per day, the insurance company wont pay for it because the 1mg pill is only approved for hair loss treatment. Preparing a list of questions before your appointment can help you make the most of your time together. Public Health. I cycled herbal androgen boosting supplements combined with intense workouts (I am a bodybuilder). Your doctor will ask you to empty your bladder, masturbate to climax and then provide a urine sample for laboratory analysis. Lol, now they banned me, just look at the reason: Dismissive of survey in first few posts; insistently advocated for dangerous and misleading article on PFS. This is a summary of the protocol which I followed for 6 months which eventually cured me. Studies show it can help slow or reverse the process of hair loss. Its like they want to hide possible solutions. When dosed properly, it can bring DHT within normal ranges very effectively. I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. I haven't had that sort of performance since I was 19 or 20 years old. Brain fog. i am so desperate.. i am a female.. i need my hair back.. but o reallu cannot undergoo all this syntomps ( i gained 20 kg on fina and dutasterde.. no muscle stranght anymore.. no way to lose weight.. i really can' t tell a lot about mental and neurological condition.. but II am so depressed too.. but probably because I am bald and fat there must be a way to take fina without sides.. there must be a way..). I just decided to get back on gear after a year off + dutasteride during that time. All of that changed in three days. Crazy. These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. Accessed Sept. 15, 2016. That fog, that mental barrier that kept me feeling a distance from myself had totally lifted. Hum. I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. PMC This after having PFS constantly for 11 years. Perhaps if I had tried it longer it would have helped more, Im not sure. TRT so thats why I went down this rabbit hole. I was on TRT when I got PFS. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: These medications help keep the bladder neck muscle closed during ejaculation. I do not think we have an answer to that question one way or the other. National Library of Medicine No interest in sex at all. Incredible! AR: androgen receptor; DHP: dihydroprogesterone; DHT: dihydrotestosterone; ER: estrogen receptor beta; PR: progesterone receptor; PROG: progesterone; T: testosterone; THP: tetrahydroprogesterone. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. there are many options including peptides, and HCG as well as clomid/arimidex. The presence of side effects during pharmacological treatment is unfortunately a quite common problem. I understand theyre trying to cover their ass but its the users responsibility if he wants to try it or not so the forum is not liable at all. Firstly, hair loss doesn't just affect older people. FOIA PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. 2018;120:143149. Examine your urine for the presence of semen after you have an orgasm. Int. Feeling dissociated and never present. When did you first begin having dry orgasms? It can prevent hair loss and decrease prostate enlargement, but not surprisingly, it can also suppress sexual function. For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Careers. When you are on TRT, your DHT levels tend to go out of the normal range and finasteride is a mechanism for bringing it back into range. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). Press question mark to learn the rest of the keyboard shortcuts. -, Basaria S., Jasuja R., Huang G., Wharton W., Pan H., Pencina K., Li Z., Travison T.G., Bhawan J., Gonthier R., Labrie F., Dury A.Y., Serra C., Papazian A., O'Leary M., Amr S., Storer T.W., Stern E., Bhasin S. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. On PFS forums, peoples dicks got 1 inch bigger when erect, here and there, they sometimes felt sexual attraction towards women. But on day 3, I felt like my old self. ._1LHxa-yaHJwrPK8kuyv_Y4{width:100%}._1LHxa-yaHJwrPK8kuyv_Y4:hover ._31L3r0EWsU0weoMZvEJcUA{display:none}._1LHxa-yaHJwrPK8kuyv_Y4 ._31L3r0EWsU0weoMZvEJcUA,._1LHxa-yaHJwrPK8kuyv_Y4:hover ._11Zy7Yp4S1ZArNqhUQ0jZW{display:block}._1LHxa-yaHJwrPK8kuyv_Y4 ._11Zy7Yp4S1ZArNqhUQ0jZW{display:none} -, Baig M.S., Kolasa-Wolosiuk A., Pilutin A., Safranow K., Baranowska-Bosiacka I., Kabat-Koperska J., Wiszniewska B. Finasteride-induced inhibition of 5alpha-reductase type 2 could lead to kidney damage-animal, experimental study. (photo). My doctor put me on 5mg daily cialis (+up to 15mg as needed before sex) clomiphene 25mg/daily anastrozole 1mg/week Addyi shockwave therapy ($3000 for 6 sessions) though this is definitely unnecessary and experimental. Arimidex 0.5mg-3mg a day as needed (keep this dose around 1mg a day, too high and you will have low estrogen, torem may prevent you from needing it, everyone is different, I may not need it anymore, I recommend taking it only as needed, Torem 60mg a day (new drug instead of hcg that is an estrogen blocker and being tested as a treatment for androgen insensitivity), DHEA 50mg 1-2X a day (sometimes 2 X if I feel I need a mood boost), Calcium D Glucarate 1500mg (as many times a day as I remember, about 3X is good), Reservatrol (whatever dose a day, its an extra), https://forum.propeciahelp.com/t/final-protocol-100-pfs-reversal-with-dht-therapy-lastpost/7845/2147. After stopping 7 weeks later (when I ran out of my proviron), things felt off for a few weeks but then after around two months I got back to my pre-PFS state. doi: 10.1016/j.urology.2018.06.022. I had all the classic symptoms. Instead of having a discussion, nope banned. Are there any brochures or other printed material that I can take home with me? Personally, I believe its become the boogeyman for a bucket list of sexual problems. For each day that goes by, I get a day of surplus inventory. I did a limited search and did not find other such claims. Feeling low-grade depression constantly. Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. You can't get worse than living with no dick dude. Mehta A, et al. Plus, get a FREE copy of the Best Diets for Cognitive Fitness. WebNeurogenesis was found to be reversed to normal 35 days after the last finasteride injection in male mice. For details, see text. Therefore, I cut the pills in half (2.5mg) and toss the other half. Sexual side effects: Loss of libido, impotence, testicular pain, testicle shrinkage, minor Peyronies (up to 10 degrees), penis pain, watery semen, Mental: Anxiety, insomnia, cognitive issues / brain fog. Keywords: The data does support that finasteride does have sexual side-effects for guys that are not on TRT while you are using it. lol. Its less than ideal though when trying to help people and you get banned for it, That forum is a farce, it seems their solution is to just wait, could help for some but others are waiting for years without improving. Ejaculation and orgasm disorders. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92. Jefferys A, et al. Anejaculation and retrograde ejaculation. Your doctor might also ask about any health problems, surgeries or cancers you've had and what medications you take. Make a donation. This site needs JavaScript to work properly. ._1sDtEhccxFpHDn2RUhxmSq{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap}._1d4NeAxWOiy0JPz7aXRI64{color:var(--newCommunityTheme-metaText)}.icon._3tMM22A0evCEmrIk-8z4zO{margin:-2px 8px 0 0} ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} Create an account to follow your favorite communities and start taking part in conversations. In addition, it has been also reported that persistent side effects may occur in some AGA patients. .LalRrQILNjt65y-p-QlWH{fill:var(--newRedditTheme-actionIcon);height:18px;width:18px}.LalRrQILNjt65y-p-QlWH rect{stroke:var(--newRedditTheme-metaText)}._3J2-xIxxxP9ISzeLWCOUVc{height:18px}.FyLpt0kIWG1bTDWZ8HIL1{margin-top:4px}._2ntJEAiwKXBGvxrJiqxx_2,._1SqBC7PQ5dMOdF0MhPIkA8{vertical-align:middle}._1SqBC7PQ5dMOdF0MhPIkA8{-ms-flex-align:center;align-items:center;display:-ms-inline-flexbox;display:inline-flex;-ms-flex-direction:row;flex-direction:row;-ms-flex-pack:center;justify-content:center} Common finasteride side effects include loss of libido, breast enlargement, erectile dysfunction (ED), and lower ejaculatory volume. Day 2 I noticed a bit more energy, but credited that to having a good night's sleep (did I mention this stuff helps you sleep better, too?) I know how I feel and I know it's working. I dont really understand why theyre like that. While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. With constant stress, your adrenals do not get a chance for recovery. Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated. I'm Just 18 and I'm Losing my Hair. If a high volume of sperm is found in your urine, you have retrograde ejaculation. Talking with a counselor might help. Alterations in orgasm are linked with lower emotional and physical satisfaction, which might lead to stress for you and your partner. The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. Fertil Steril. decreased libido * (sex drive) erectile dysfunction *. Management of the dry ejaculate: A systematic review of aspermia and retrograde ejaculation. Midodrine, a medicine that constricts blood vessels. The article stated proviron was the best potential cure in his opinion. I am not aware of the use of Human Growth Hormone in the treatment for Post Finasteride Syndrome. reading time: 43 Merck developed finasteride in the 1980s. ._3-SW6hQX6gXK9G4FM74obr{display:inline-block;vertical-align:text-bottom;width:16px;height:16px;font-size:16px;line-height:16px} If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. I also tried testosterone treatment but it had almost no effect regardless of dosage. Inability to concentrate. The results have been amazing and far too great to chalk it up to just being a placebo. Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. ._2ik4YxCeEmPotQkDrf9tT5{width:100%}._1DR1r7cWVoK2RVj_pKKyPF,._2ik4YxCeEmPotQkDrf9tT5{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center}._1DR1r7cWVoK2RVj_pKKyPF{-ms-flex-pack:center;justify-content:center;max-width:100%}._1CVe5UNoFFPNZQdcj1E7qb{-ms-flex-negative:0;flex-shrink:0;margin-right:4px}._2UOVKq8AASb4UjcU1wrCil{height:28px;width:28px;margin-top:6px}.FB0XngPKpgt3Ui354TbYQ{display:-ms-flexbox;display:flex;-ms-flex-align:start;align-items:flex-start;-ms-flex-direction:column;flex-direction:column;margin-left:8px;min-width:0}._3tIyrJzJQoNhuwDSYG5PGy{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center;width:100%}.TIveY2GD5UQpMI7hBO69I{font-size:12px;font-weight:500;line-height:16px;color:var(--newRedditTheme-titleText);white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.e9ybGKB-qvCqbOOAHfFpF{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center;width:100%;max-width:100%;margin-top:2px}.y3jF8D--GYQUXbjpSOL5.y3jF8D--GYQUXbjpSOL5{font-weight:400;box-sizing:border-box}._28u73JpPTG4y_Vu5Qute7n{margin-left:4px} Post-finasteride syndrome (PFS) is defined as a syndrome with symptoms that can include erectile dysfunction (ED), decreased libido, fatigue, penile and scrotal atrophy and numbness, gynecomastia, muscle atrophy, anxiety, blunted affect, and emotional sensitivity in patients who have taken 5-reductase inhibitors such as finasteride or Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in @keyframes _1tIZttmhLdrIGrB-6VvZcT{0%{opacity:0}to{opacity:1}}._3uK2I0hi3JFTKnMUFHD2Pd,.HQ2VJViRjokXpRbJzPvvc{--infoTextTooltip-overflow-left:0px;font-size:12px;font-weight:500;line-height:16px;padding:3px 9px;position:absolute;border-radius:4px;margin-top:-6px;background:#000;color:#fff;animation:_1tIZttmhLdrIGrB-6VvZcT .5s step-end;z-index:100;white-space:pre-wrap}._3uK2I0hi3JFTKnMUFHD2Pd:after,.HQ2VJViRjokXpRbJzPvvc:after{content:"";position:absolute;top:100%;left:calc(50% - 4px - var(--infoTextTooltip-overflow-left));width:0;height:0;border-top:3px solid #000;border-left:4px solid transparent;border-right:4px solid transparent}._3uK2I0hi3JFTKnMUFHD2Pd{margin-top:6px}._3uK2I0hi3JFTKnMUFHD2Pd:after{border-bottom:3px solid #000;border-top:none;bottom:100%;top:auto} Is Post Finasteride Syndrome Real? When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. .ehsOqYO6dxn_Pf9Dzwu37{margin-top:0;overflow:visible}._2pFdCpgBihIaYh9DSMWBIu{height:24px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu{border-radius:2px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:focus,._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:hover{background-color:var(--newRedditTheme-navIconFaded10);outline:none}._38GxRFSqSC-Z2VLi5Xzkjy{color:var(--newCommunityTheme-actionIcon)}._2DO72U0b_6CUw3msKGrnnT{border-top:none;color:var(--newCommunityTheme-metaText);cursor:pointer;padding:8px 16px 8px 8px;text-transform:none}._2DO72U0b_6CUw3msKGrnnT:hover{background-color:#0079d3;border:none;color:var(--newCommunityTheme-body);fill:var(--newCommunityTheme-body)} Most men eventually develop some type of prostate problem, and when they do there are usually no easy solutions. I took intramuscular injections of HCG every 3 a 5 days 1500 to 3000 ui by injections for 1 months only, and after that some Clomid for 10 days 2 pills by day It helped relaunch the natural testorene levels so my libido increased again i am now totally satisfied with my health :slight_smile: https://forum.propeciahelp.com/t/i-believe-i-have-been-cured-by-accident/4054, Yes After nearly 4 years of suffering, I have finally & fully recovered from Post Finasteride Syndrome, All my symptoms have subsided and improved with this method which takes a while but I am fully functional. For details, see text. If so, how long have you been trying to conceive? Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. Do you have cloudy urine after an orgasm? I tried just about everything over 11 years. Therefore, I cut the pills in half (2.5mg) and toss the other half. -, Baas W.R., Butcher M.J., Lwin A., Holland B., Herberts M., Clemons J., Delfino K., Althof S., Kohler T.S., McVary K.T. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. Do you ever ejaculate semen when you have an orgasm, or do you have a dry orgasm every time? breast tenderness. https://www.hairlosstalk.com/interact/threads/how-i-cured-my-problem-with-post-finasteride-syndrome.125634/. If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions. ._1QwShihKKlyRXyQSlqYaWW{height:16px;width:16px;vertical-align:bottom}._2X6EB3ZhEeXCh1eIVA64XM{margin-left:3px}._1jNPl3YUk6zbpLWdjaJT1r{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;padding:0 4px}._1jNPl3YUk6zbpLWdjaJT1r._39BEcWjOlYi1QGcJil6-yl{padding:0}._2hSecp_zkPm_s5ddV2htoj{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;margin-left:0;padding:0 4px}._2hSecp_zkPm_s5ddV2htoj._39BEcWjOlYi1QGcJil6-yl{padding:0}._1wzhGvvafQFOWAyA157okr{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;box-sizing:border-box;line-height:14px;padding:0 4px}._3BPVpMSn5b1vb1yTQuqCRH,._1wzhGvvafQFOWAyA157okr{display:inline-block;height:16px}._3BPVpMSn5b1vb1yTQuqCRH{background-color:var(--newRedditTheme-body);border-radius:50%;margin-left:5px;text-align:center;width:16px}._2cvySYWkqJfynvXFOpNc5L{height:10px;width:10px}.aJrgrewN9C8x1Fusdx4hh{padding:2px 8px}._1wj6zoMi6hRP5YhJ8nXWXE{font-size:14px;padding:7px 12px}._2VqfzH0dZ9dIl3XWNxs42y{border-radius:20px}._2VqfzH0dZ9dIl3XWNxs42y:hover{opacity:.85}._2VqfzH0dZ9dIl3XWNxs42y:active{transform:scale(.95)} Make a list of all medications, vitamins and supplements that you're taking. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. I didnt feel any improvement and felt worse during that period but after that period I healed which is very weird. Finasteride is available as a lower-cost generic. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? J. Clin. Ive seen this several times over there. In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. I will tell you how I solved my problem with post-finasteride syndrome, which produces no erections or little libido even if you have stopped taking the famous drug years ago. https://forum.propeciahelp.com/t/cured-after-11-years/42363. Plentiful in opinions, short on facts. A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. I was able to have 8 sexual encounters in 1 week with different people - I felt no PFS symptoms whatsoever My muscle mass and body fat composition is now normal, my semen thickened, Peyronies stabilized, penis pain subsided, testicular pain is rare cognitive issues are resolved, and overall I think I've bounced back almost entirely. Here's some information to help you get ready for your appointment, and what to expect from your doctor. I read the thing on Healthline where it says it doesn't raise testosterone in humans. 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. At first, I felt absolutely miserable when doing so, it is the worst Ive felt in my life and I was unable to do almost anything but after some weeks it became more tolerable as the receptors lost some of their sensitivity. I think it took 6 months before i felt ready to meet a girl again. I have been prescribed a 2.5% DHT gel that is applied to the shoulders and forehead once a day. After 4 months of no progress whatsoever I tried the regimen that saved me - at least thats the only explanation I have. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. It looked like it had been around the world a few times. I cannot say enough about this. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. The information on RealSelf is intended for educational purposes only. You're right. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. I have not made any drastic life changes since beginning this. Oh, and to not need to play with and shake the life out of my penis to wake it up. Elsevier; 2021. https://www.clinicalkey.com. Energy-boosting coffee alternatives: What to know. Unable to load your collection due to an error, Unable to load your delegates due to an error. In: Ferri's Clinical Advisor 2022. 2023 by The President and Fellows of Harvard College, Do not sell my personal information | Privacy Policy. | How To Diagnose And Reverse It. Est. 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. Clinical features reported in patients affected by post-finasteride syndrome. https://forum.propeciahelp.com/t/joekool-s-story-long-term-hcg/46717. Even my genitals began to grow normal size again. At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). As a 5-alpha reductase inhibitor, finasteride works by inhibiting the effects of the enzyme thats responsible for converting testosterone into dihydrotestosterone (DHT). Accessed Oct. 28, 2021. I tried proviron for a short time but it made me feel worse. Should I be concerned? Although these drugs are generally well tolerated, many reports described adverse effects in men during treatment, such as sexual dysfunction and mood alteration. To diagnose retrograde ejaculation, your doctor may: If you have dry orgasms, but your doctor doesn't find semen in your bladder, you might have a problem with semen production. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. The mods on that forum are fascists and dont allow the opinion and theory of other people. 2016;93:9. I am not aware or scientific evidence that back this up at this time. If I do achieve an erection it has to be constantly stimulated or it goes away FAST and even thats not a guarantee. Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. These anecdotes report success using steroids or ancillaries. 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